Occupational Diseases of Pharmacists & Pharmaceutical Workers

OA = Occupational Asthma
ACD = Allergic Contact Dermatitis
CU = Contact Urticaria
PACD = Photoallergic Contact Dermatitis
PSA (Not occupational) = Photosensitivity to a Systemic Agent (Photodrug Reaction)
ANTIBIOTICS
Ampicillin OA CU
Bacitracin ACD CU
Cephalosporins OA CU
Chloramphenicol ACD CU
Ciprofloxin PSA
Gentamycin ACD CU
Griseofulvin PSA
Iodochlorhydroxyquin (Vioform) ACD CU
Isoniazid OA
Lincomycin ACD
Mezlocillin CU
Nalidixic acid PSA
Neomycin ACD CU
Nitrofurazone (Furacin) ACD
Pencillin OA CU
Spectinomycin ACD
Spiramycin OA
Streptomycin CU
Sulfanilamide PSA PACD
Tetracyclines PSA OA
Thimerosal (Merthiolate) ACD
Virginiamycin ACD CU
ANIMAL-FEED ADDITIVES
Amprolium OA ACD
Clopidol ACD
Ethoxyquin ACD
Furaltadone ACD
Furazolidone ACD
Olaquindox ACD
Thiabendazole ACD
Tylosin OA ACD
CHEMOTHERAPEUTIC AGENTS
Azathioprine (Imuran) ACD
Cisplatin CU
Dacarbazine PSA
5-Fluorouracil PSA
Mitoxantrone OA
Vinblastine PSA
DIURETICS
Furosemide PSA
Hydrochlorothiazide PSA
ANTIHYPERTENSIVES
Alprenolol ACD
Hydralazine OA ACD
Labetalol ACD
Methyldopa OA
Oxprenolol ACD
Propanolol ACD
NSAIDS
Benzydamine (Difflam) ACD PACD
Naproxen (Naprosyn) PSA
Oxaprozin (Daypro) PSA
Piroxicam (Feldene) ACD PSA
OTHER AGENTS
Amiodarone PSA
Azoperone ACD
Benzocaine ACD CU
Cimetidine OA
Chlorpromazine PSA PACD CU
Codeine OA ACD
Disulfiram (Antabuse) ACD
Famotidine (Pepcid) ACD
Hematoporphyrin PSA
Ipecac OA
Morphine OA ACD
Penicillamine OA
Promethazine PACD CU
Propacemetol ACD
Phenothiazine PACD CU
Procaine hydrochloride ACD
Psoralen PSA
Psyllium OA (also in nurses)
Quinidine ACD PSA
Ranitidine ACD
Salbutamol intermediate OA
Tetracaine ACD
Tolbutamide PSA
 
 
 
Sensitization to drugs occurs during production and use: 
1. Handling by pharmaceutical chemists and technicians;
2. Packaging and cleaning by manufacturing workers;
3. Hand-compounding by pharmacists;
4. Mixing animal feeds by farmers;
5. Crushing tablets, mixing powders, or preparing lypholized solutions by nurses;
6. Applying topical drugs to patients by nurses or physical therapists; [Kanerva, p. 479]

 

References: Marks, Malo and Kanerva and Kanerva 2004

ACD: Chemicals ] ACD: Biologicals ] Contact Urticaria ] [ OA and ACD: Drugs ]

  Revised April 15, 2007

Home Up OA and ACD: Dyes

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