1,2,3,4-Tetrahydronaphthalene

Synonyms

Bacticin; Benzocyclohexane; Naphthalene 1,2,3,4-tetrahydride; Naphthalene, 1,2,3,4-tetrahydro-; Tetrahydronaphthalene; Tetralina [Polish]; Tetraline; Tetranap; delta(sup 5,7,9)-Naphthantriene; Tetralin; [ChemIDplus]

Category

Naphthalenes

Description

Light-colored liquid; [CAMEO]

Sources/Uses

Used in the solvent, paint, varnish, and rubber industries; tetralin is used in shoe polish and floor wax; [HSDB]

Comments

Listed in table of "Methemoglobinemia-inducing agents: industrial, environmental, and pharmaceutical"; [Sullivan, p. 729]; Tetralin is a skin and mucous membrane irritant. When used in poorly ventilated areas, tetralin may cause central nervous system depression. Ingestion of tetralin has caused green urine and laboratory evidence of liver and kidney injury. [HSDB] A skin, eye, and respiratory tract irritant; Inhalation of high concentrations may cause CNS effects; May cause kidney injury; [ICSC]

Biomedical References

2 ppm

0.368 mm Hg

LC50 (guinea pigs) = 275 ppm

Explanatory Notes

Flash point = 82 deg C; VP from HSDB;

high ambient temp required

MetHgb is secondary toxic effect

Acute solvent syndrome

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases

Occupational diseases associated with exposure to this agent:

• Encephalopathy, chronic solvent
• Solvents, acute toxic effect

Processes

Industrial Processes with risk of exposure:

• Painting (Solvents)