m-Nitroaniline

Agent Name
m-Nitroaniline
CAS Number
99-09-2
Formula
C6-H6-N2-O2
Major Category
Nitrogen Compounds
m-Nitroaniline formula graphical representation
Synonyms
1-Amino-3-nitrobenzene; 3-Aminonitrobenzene; 3-Nitroaniline; 3-Nitrobenzenamine; 3-Nitrophenylamine; Amarthol Fast Orange R Base; Aniline, m-nitro-; Azobase MNA; Benzenamine, 3-nitro-; C.I. 37030; C.I. Azoic Diazo Component 7; CI 37030; CI Azoic Diazo Component 7; Daito Orange Base R; Devol Orange R; Diazo Fast Orange R; Fast Orange Base R; Fast Orange M Base; Fast Orange MM Base; Fast Orange R Base; Fast Orange R Salt; Hiltonil Fast Orange R Base; MNA; Naphtoelan Orange R Base; Nitranilin; Orange Base Irga I; m-Aminonitrobenzene; m-Nitraniline; m-Nitroaminobenzene; m-Nitroaniline; m-Nitrophenylamine; [ChemIDplus] UN1661
Category
Nitroanilines
Description
Yellow needle-like crystals; burning, sweet odor; [CHEMINFO]
Sources/Uses
Used as a "color test for pine wood" and in the synthesis of organic chemicals; [HSDB]
Comments
m-Nitroaniline is in the ACGIH table of "Industrial Chemicals for Which Methemoglobin Formation is the Principal Cause of Toxicity." It emits toxic fumes of nitrogen oxides when heated. Methemoglobinemia has been reported after acute exposure and liver injury after chronic exposure. m-Nitroaniline is toxic after ingestion, inhalation, and skin exposure. [HSDB] Can induce methemoglobinemia; [ICSC]
Biomedical References

Exposure Assessment

BEI
Methemoglobin in blood = 1.5% of hemoglobin during or at end of shift. [ACGIH]
Vapor Pressure
9.56E-05 mm Hg
Explanatory Notes
mp = 114 deg C; bp = 306 deg C (decomposes); Flash point = 199 deg C; VP from HSDB;

Adverse Effects

Methemoglobinemia
MetHgb is primary toxic effect
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent: