Pinacolyl alcohol

Agent Name
Pinacolyl alcohol
Alternative Name
3,3-Dimethyl-2-butanol
CAS Number
464-07-3
Formula
C6-H14-O
Major Category
Solvents
Pinacolyl alcohol formula graphical representation
Synonyms
2,2-Dimethyl-3-butanol; tert-Butyl methyl carbinol; 2-Butanol, 3,3-dimethyl-; 3,3-Dimethylbutan-2-ol; 3,3-Dimethyl-2-butanol; [ChemIDplus] Pinacoline alcohol; [Sigma-Aldrich MSDS] UN1987
Category
Alcohols (<C12)
Description
Colorless liquid; mp = 5.6 deg C; [HSDB] Clear light yellow liquid; [Sigma-Aldrich MSDS]
Sources/Uses
Used to make chemical warfare agents (i.e. Soman); [HSDB]
Comments
Causes CNS depression and nephrotoxicity in experimental animals; Clinical effects likely to be similar to ethanol, based on closely related structure; Ataxia, mild hypoxemia, hypercapnia, lachrymation, depressed respiration and motor activity, increased cholesterol and bilirubin, and acute tubular necrosis and renal failure observed in inhalation studies of rats; [Reference #1] May cause irritation; [Sigma-Aldrich MSDS]
Reference Link #1
INCHEM: Pinacolyl alcohol (PIM 981 - 2001)
Biomedical References
Search PubMed

Exposure Assessment

Vapor Pressure
8.81 mm Hg
Lethal Concentration
LCLo (rat) = 3,600 ppm
Explanatory Notes
LC50 (rat) = 15,000 mg/m3; [RTECS] The Guide in the Emergency Response Guidebook is for "Alcohols, n.o.s." VP from ChemIDplus;

Adverse Effects

Neurotoxin
Acute solvent syndrome

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent: