Fluorescein-5-isothiocyanate

Agent Name
Fluorescein-5-isothiocyanate
Alternative Name
FITC
CAS Number
3326-32-7
Formula
C21-H11-N-O5-S
Major Category
Dyes
Fluorescein-5-isothiocyanate formula graphical representation
Synonyms
Spiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one, 3',6'-dihydroxy-5-isothiocyanato-; [ChemIDplus] 3',6'-dihydroxy-5-isothiocyanatospiro(isobenzofuran-1(3H),9'-(9H)xanthen)-3-one; FITC; [Merck Index]
Category
Indicator Dyes
Description
Orange solid; [Merck Index] Orange powder; [Alfa Aesar MSDS]
Sources/Uses
Used as a fluorescent indicator to probe biological systems and monitor sewage; [Merck Index]
Comments
Causes cutaneous sensitization (experimental) and effects on inflammation in 3-day intermittent dermal studies of mice; [RTECS] May cause irritation; May cause skin and respiratory sensitization; [Alfa Aesar MSDS]
Reference Link #1
Systemic migration of dendritic cells during contact sensitization.
Biomedical References
Search PubMed

Exposure Assessment

Adverse Effects

Skin Sensitizer
Yes

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent: