4,4'-Methylenebis(2,6-di-tert-butylphenol)

Synonyms

2,2',6,6'-Tetra-tert-butyl-4,4'-methylenediphenol; 4,4'-Methylenebis(2,6-bis(1,1-dimethylethyl)phenol); 4,4'-Methylenebis(2,6-di-t-butylphenol); Antioxidant E 702; Binox M; Di(4-hydroxy-3,5-di-tert-butylphenyl)methane; E 702; Ethyl 702; Etil 702; Ionox 220; Ionox 220 Antioxidant; L 3MB1; LZ-MB 1; MB 1 (Antioxidant); MB 1 (antioxidant) (VAN); Phenol, 4,4'-methylenebis(2,6-di-tert-butyl-; Phenol, 4,4'-methylenebis(2,6-bis(1,1-dimethylethyl)-; [ChemIDplus] 4,4'-Dihydroxy-3,3',5,5'-tetra-tert-butyl-diphenylmethan; Alkylated phenol; Ethanox 702; [IUCLID]

Category

Other Aromatic Compounds

Description

White or yellow powder; [Alfa Aesar MSDS]

Sources/Uses

Used in the fuel, polymers, and lubricant blending industries; Used as an antioxidant additive in petroleum-based lubricants; [IUCLID]

Comments

A skin and eye irritant in rabbits; No mortality or gross lesions observed in oral lethal-dose study of rats at 5,000 mg/kg; Another lethal-dose study of rats produced increasing severity of hepatic degeneration in animals that died (doses of 4,700-36,000 mg/kg); No mortality or symptoms of systemic toxicity observed in dermal lethal-dose study of rats at doses up to 36,000 mg/kg; [IUCLID] Causes ulceration or bleeding from the large intestine and fibrous hepatitis (cirrhosis, post necrotic scarring) in 2-year constant feeding studies of dogs; [RTECS] A skin and strong eye irritant; [Alfa Aesar MSDS] See "2,2'-Methylenebis(6-t-butyl-4-ethylphenol)."

Biomedical References

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Other Information

No other related information on this agent was found.