Barbituric acid
Agent Name
Barbituric acid
CAS Number
67-52-7
Formula
C4-H4-N2-O3
Major Category
Nitrogen Compounds
Synonyms
2,4,6(1H,3H,5H)-Pyrimidinetrione; 2,4,6-Pyrimidinetriol; 2,4,6-Pyrimidinetrione; 2,4,6-Trihydroxypyrimidine; 2,4,6-Trioxohexahydropyrimidine; 6-Hydroxyuracil; Hydrouracil, 6-hydroxy-; Malonylurea; Pyrimidinetriol; Pyrimidinetrione; Urea, N,N'-(1,3-dioxo-1,3-propanediyl)-; [ChemIDplus]
Category
Pyrimidines
Description
White powder; [Alfa Aesar MSDS]
Sources/Uses
Used to make plastics and pharmaceuticals; [Merck Index] Discovered in 1864, barbituric acid was the first barbiturate drug--used as a sedative and anticonvulsant; [Wikipedia]
Comments
"Unsubstituted barbituric acid has no hypnotic properties." [Merck Index] Causes somnolence, impaired liver function tests, depressed renal function tests, and other changes in urine composition in acute inhalation studies of rats; Causes somnolence and ataxia in oral lethal-dose studies of mice and rats; Causes somnolence and impaired liver function tests in 30-day intermittent inhalation studies of rats; [RTECS] An irritant; [Alfa Aesar MSDS]
Biomedical References
Exposure Assessment
Vapor Pressure
2.17E-09 mm Hg
Adverse Effects
Neurotoxin
Other CNS neurotoxin
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.