ISOTHIAZOLINONES

Synonyms

CLASSES

Category

Biocides/Disinfectants

Sources/Uses

Isothiazolinones are used as preservatives, biocides, and disinfectants.

Comments

One of the isothiazolinones is methylchloroisothiazolinone/methylisothiazolinone (Kathon CG). It is a mixture of these two isothiazolinone. ". . . Nethercott et al. found that 11 of 27 (41%) metalworkers with eczematous dermatitis in an engine parts manufacturing plant developed allergic contact dermatitis due to Kathon 886 MW in metal-working fluids." [Marks, p. 102-3] Occupational asthma reported in an isothiazolinone manufacturing plant; [Malo]

Biomedical References

Yes

Yes

Diseases

Occupational diseases associated with exposure to this agent:

• Asthma, occupational
• Contact dermatitis, allergic

Processes

Industrial Processes with risk of exposure:

• Dressing Hair
• Leather Tanning and Processing
• Metal Machining
• Painting (Pigments, Binders, and Biocides)
• Pulp and Paper Processing
• Using Disinfectants or Biocides

Activities

Activities with risk of exposure:

• Ceramics making