beta-Cyclodextrin

Agent Name
beta-Cyclodextrin
CAS Number
7585-39-9
Formula
C42-H70-O35
Major Category
Biological Agents
beta-Cyclodextrin formula graphical representation
Synonyms
Betadex; Cycloheptaamylose; Cycloheptaglucan; Cycloheptaglucosan; Cyclomaltoheptaose; Dextrin, beta-cyclo; Kleptose; Kleptose B; Rhodocap N; Ringdex B; Ringdex BL; Schardinger beta-dextrin; beta-Cycloamylose; beta-Cycloheptaamylose; beta-Dextrin; Cycloheptapentylose; [ChemIDplus] betaCD; BCD; beta-Schardinger dextrin; Cyclodextrin C; [JECFA]
Category
Polysaccharides
Description
White virtually odorless solid; [JECFA] White powder; [Sigma-Aldrich MSDS]
Sources/Uses
Permitted for use as an inert ingredient in non-food pesticide products; [EPA] Used as flavoring agent and formulation aid; [FDA] Used as a thickening agent and an encapsulation agent for food additives, flavoring, and vitamins; [JECFA]
Comments
Composed of 7 glucose units joined together; Acceptable daily intake (ADI) of 0-5 mg/kg; [JECFA] Causes zonal hepatitis and acute tubular necrosis in 52-week constant oral studies of rats; Causes diffuse and zonal hepatitis in 7-week constant oral studies of rats; [RTECS] Causes mild skin and eye irritation in rabbits; Not a skin sensitizer in guinea pigs; [Sigma-Aldrich MSDS] See "alpha-Cyclodextrin."
Biomedical References

Exposure Assessment

Lethal Concentration
LC50 (rat) > 4,900 mg/m3/4hr

Adverse Effects

Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases, Processes, and Activities Linked to This Agent

Other Information
No other related information on this agent was found.