Clostridium botulinum neurotoxins
Agent Name
Clostridium botulinum neurotoxins
CAS Number
93384-43-1; 93384-44-2
Major Category
Biological Agents
Synonyms
BoNT-A; Botulinum Neurotoxin Type A; Botulinum neurotoxin; Clostridium botulinum neurotoxin A; Clostridium botulinum neurotoxin B; Clostridium botulinum neurotoxin C1; Clostridium botulinum neurotoxin D; Clostridium botulinum neurotoxin E; Clostridium botulinum neurotoxin F; Clostridium botulinum neurotoxin G; Neurotoxin, Clostridium botulinum; [ChemIDplus]
Category
Bacterial Toxins
Sources/Uses
Seven antigenically distinct neurotoxins produced by the spores of Clostridium botulinum; Types A, B, E, and F affect humans by interfering with the release of acetylcholine at peripheral nerve endings; [Merck Manual]
Comments
"Symptoms are symmetric cranial nerve palsies accompanied by a symmetric descending weakness and flaccid paralysis without sensory deficits." [Merck Manual, p. 1464] Causes ptosis and changes in extra-ocular muscles in acute intracerebral studies of mice; [RTECS] See "Botulism" at https://iddx.com/.
Other Information
No other related information on this agent was found.