alpha-Methyldopa

Agent Name
alpha-Methyldopa
CAS Number
555-30-6
Formula
C10-H13-N-O4
Major Category
Other Uses
Synonyms
alpha-Methyl-DOPA; L-2-Amino-3-(3,4-dihydroxyphenyl)-2-methylpropionic acid; Medopa; Nr.C 2294; Presolisin; Sedometil; Sembrina; L-Methyldopa; L-alpha-Methyldopa; alpha-Methyl-L-dopa; MK 351; Presinol; 3-Hydroxy-alpha-methyl-L-tyrosine; L-2-Amino--2-methyl-3-(3,4-dihydroxyphenyl)propionic acid; Aldometil; Aldomin; alpha Medopa; Hyperpax; Medomet; Medopren; Methoplain; L-(-)-beta-(3,4-Dihydroxyphenyl)-alpha-methylalanine; L-(-)-3-(3,4-Dihydroxyphenyl)-2-methylalanine; L-alpha-Methyl-3,4-dihydroxyphenylalanine; L-(-)-alpha-Methyl-beta-(3,4-dihydroxyphenyl)alanine; alpha-Methyl-L-3,4-dihydroxyphenylalanine; alpha-Methyl-beta-(3,4-dihydroxyphenyl)-L-alanine; AMD; Bayer 1440 L; Baypresol; Dopamet; Dopatec; Dopegyt; L-(alpha-Md); (-)-Methyldopa; 3-(3,4-Dihydroxyphenyl)-2-methyl-L-alanine; Aldomet; Methyl-DOPA; alpha-Methyldopa; [ChemFinder]
Category
Pharmaceuticals
Comments
Asthma reported in the pharmaceutical industry; [Malo] As an oral medication, methyldopa is used to treat hypertension. Many side effects have been reported after ingestion of therapeutic doses, including immune hemolytic anemia and drug-induced hepatitis. [HSDB]
Biomedical References

Adverse Effects

Asthma
Yes
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent: