Dimethyl malonate
Agent Name
Dimethyl malonate
CAS Number
108-59-8
Formula
C5-H8-O4
Major Category
Other Classes
Synonyms
Dimethyl 1,3-propanedioate; Dimethyl malonate; Dimethyl propanedioate; Malonic acid, dimethyl ester; Propanedioic acid, 1,3-dimethyl ester; Propanedioic acid, dimethyl ester; [ChemIDplus] DMM; Dimethylmalonate; [OECD SIDS: Malonic Acid Diesters - 2005]
Category
Esters, Other
Description
Liquid; [Merck Index] Colorless liquid with an ester-like odor; [OECD SIDS: Malonic Acid Diesters - 2005]
Sources/Uses
Naturally occurring as a volatile in fruits such as pineapples, bananas, and blackberries; Used as an intermediate for agrochemicals, pharmaceuticals, industrial chemicals, and other compounds; [OECD SIDS: Malonic Acid Diesters - 2005]
Comments
Causes no skin irritation and mild to moderate eye irritation in rabbits; No adverse effects observed in oral or dermal lethal-dose studies of rats (LD50s > 2,000 mg/kg); Reversible hepatocellular hypertrophy (considered indicative of liver metabolism rather than systemic toxicity) observed in an oral repeated-dose study of rats at the highest tested dose (1,000 mg/kg/day); No evidence of reproductive toxicity, developmental toxicity, or mutagenicity; [OECD SIDS: Malonic Acid Diesters - 2005] May cause irritation; [Alfa Aesar MSDS]
Biomedical References
Exposure Assessment
Vapor Pressure
14.7 mm Hg
Explanatory Notes
VP = 0.37 mm Hg at 20 deg C; [OECD SIDS: Malonic Acid Diesters - 2005] VP from ChemIDplus;
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.