Imidazolidinyl urea

Synonyms

Imidurea; N,N''-Methylenebis(N'-(3-(hydroxymethyl)-2,5-dioxo-4-imidazolidin- yl)urea; Urea, N,N''-methylenebis(N'-(3-(hydroxymethyl)-2,5-dioxo-4-imidazolidin- yl)-; 1,1'-Methylenebis(3-(3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)urea); Germall 115; Methanebis(N,N'-(5-ureido-2,4-diketotetrahydroimidazole)-N,N-dimethylol); N,N''-Methylenebis(N'-(1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)urea); N,N'-Methylenebis(N'-(3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)urea); N,N''-Methylenebis(N'-(3-(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl)urea); Urea, N,N''-methylenebis(N'-(1-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)-; Urea, N,N''-methylenebis(N'-(3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)-; [ChemIDplus]

Category

Biocides/Disinfectants

Description

Exists as the monohydrate: White odorless solid; [Merck Index]

Sources/Uses

Used as a biocide in cosmetics with 0.6% the maximum allowable concentration in the EU; [Kanerva, p. 398, 407] Used as an antimicrobial preservative in cosmetics and topical pharmaceuticals; [Merck Index] One of the most widely used preservative systems (especially in combination with parabens) in the world and often found in cosmetics; [NTP]

Comments

A formaldehyde releaser used in cosmetics; It can cause allergic contact dermatitis; "Rinse off products in general will have a low risk of causing allergic contact dermatitis." [Kanerva, p. 398-404] Reports of contact dermatitis from its use in cosmetics; No contact sensitivity observed in several studies; [NTP] A irritant; [Aldrich MSDS]

Biomedical References

LC50 (rat) > 5,000 mg/m3/1hr

Yes

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic

Processes

Industrial Processes with risk of exposure:

• Using Disinfectants or Biocides