1,2-Dimethylhydrazine

Agent Name
1,2-Dimethylhydrazine
CAS Number
540-73-8
Formula
C2-H8-N2
Major Category
Nitrogen Compounds
1,2-Dimethylhydrazine formula graphical representation
Synonyms
1,2-DMH; 1,2-Dimethyl-hydrazine; 1,2-Dimethylhydrazin [German]; DMH; Hydrazine, 1,2-dimethyl-; Hydrazomethane; N,N'-Dimethylhydrazine; SDMH; Symetryczna dwumetylohydrazyna; Symetryczna dwumetylohydrazyna [Polish]; Symmetrical-dimethylhydrazine; sym-Dimethylhydrazine; Dimethylhydrazine, symmetrical; [ChemIDplus] UN2382
Category
Hydrazines
Description
Colorless liquid with a fishy or ammonia-like odor; [NIOSH] Hygroscopic liquid; Fumes and gradually turns yellow in air; [Merck Index]
Sources/Uses
Used in research and not used commercially; [HSDB] Used in the production of photographic chemicals; [CAMEO]
Comments
Liquid causes second or third degree burns after short contact; [CHRIS] Patients poisoned by hydrazines may develop methemoglobinemia and liver injury; Emergency treatment: "Hydrazines"; [HSDB] Inhalation of hydrazine compounds in high concentrations can induce seizures and coma; Corrosive to skin; [Merck Index] Toxic after absorption through skin; Inhalation of high concentrations can induce pulmonary irritation and edema; [CAMEO] A strong reducing agent; An eye and respiratory tract irritant; May injure liver; Can be absorbed through skin; The kidney is target organ in experimental animals; [ICSC] Danger of skin sensitization; [MAK] Causes convulsions and dyspnea in lethal-dose inhalation studies of rats; [RTECS]
Biomedical References

Exposure Assessment

TIH
Yes
Vapor Pressure
69.9 mm Hg
Lethal Concentration
LC50 (rat) = 280 ppm/4hr
Explanatory Notes
Highly flammable; Flash point = 5 deg F; [CAMEO] VP from HSDB;
Reference Link #2

Adverse Effects

Skin Sensitizer
Yes
Toxic Pneumonitis
Yes
Methemoglobinemia
MetHgb is secondary toxic effect
Neurotoxin
Other CNS neurotoxin
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Dermatotoxin
Skin burns
IARC Carcinogen
Probable (2a)

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent: