Fluorobenzene

Synonyms

Monofluorobenzene; Phenyl fluoride; Benzene, fluoro-; [ChemIDplus] Benzene fluoride; MFB; [CAMEO] UN2387

Category

Other Solvents

Description

Liquid with an odor of benzene; [Merck Index] Colorless liquid with an aromatic odor; [Alfa Aesar MSDS]

Sources/Uses

Used to control carbon content in steel manufacturing, as an identification reagent for plastic and resin polymers, and as an intermediate for insecticides and larvicides; [NTP] Used as an intermediate for pharmaceuticals, pesticides, and other organic compounds; [EPA - PPRTV]

Comments

Causes general anesthesia in inhalation lethal-concentration studies of mice; [RTECS] A 28-day inhalation study of rats produced adaptive liver changes (not considered toxicologically significant), and increased fluoride concentrations in bones and teeth; Not likely to cause developmental toxicity or teratogenicity, based on software modeling and a structurally similar compound (chlorobenzene); [EPA ChAMP: Submissions - Submission] May cause smarting and reddening of skin if spilled and allowed to remain on clothes; Vapor exposure may cause coughing, transient anesthesia, and CNS depression; Chronic inhalation exposure may cause lung, liver, and kidney injury; [CHRIS] A skin, eye, nose, and throat irritant; [ToxPlanet: FAHG] An irritant; [NTP] A mild skin and strong eye irritant; Vapors may cause narcotic effects; [Alfa Aesar MSDS] See "Chlorobenzene."

Biomedical References

77.2 mm Hg

LC50 (rat) = 26,908 mg/m3

may ignite at ambient temp

Acute solvent syndrome

Diseases

Occupational diseases associated with exposure to this agent:

• Solvents, acute toxic effect

Processes

Industrial Processes with risk of exposure:

• Steel Producing