Chlorotrimethylsilane
Agent Name
Chlorotrimethylsilane
Alternative Name
Trimethylchlorosilane
CAS Number
75-77-4
Formula
C3-H9-Cl-Si
Major Category
Toxic Gases & Vapors
Synonyms
Monochlorotrimethylsilicon; Silane, chlorotrimethyl-; Silane, trimethylchloro-; Silicane, chlorotrimethyl-; Silylium, trimethyl-, chloride; TL 1163; Trimethyl chlorosilane; Trimethylchlorosilane; Trimethylsilyl chloride; [ChemIDplus] UN1298
Category
Chlorosilanes
Description
Colorless liquid with a pungent odor; [ICSC]
Sources/Uses
Used in the production of silicone fluids and water-repellent compounds; [HSDB] Manufactured, stored, and used in specialized facilities with airtight systems with an inert atmosphere and collection and process systems for ventilation gases; [IUCLID]
Comments
Corrosive to skin; [Quick CPC] A lachrymator; [HSDB] Corrosive to skin, eye, and respiratory tract; High inhalation exposure can cause pulmonary edema; [ICSC] Toxicity due to release of HCl during hydrolysis; [AIHA] Reacts violently and exothermically with water evolving hydrogen chloride gas (heat of reaction may ignite combustible materials); [CAMEO]
Biomedical References
Exposure Assessment
TIH
Yes
Dangerous When Wet
Yes
Vapor Pressure
234 mm Hg
Lethal Concentration
LC50 (rat) = 13,175 mg/m3/1hr
Explanatory Notes
Not TIH in land-based spills, but TiH substance released when spilled in water; [ERG 2016] Flash point = -28 deg C; VP from HSDB;
NFPA
may ignite at ambient temp
ERPG-1
3 ppm
ERPG-2
20 ppm
ERPG-3
150 ppm
WEEL
Ceiling = 5 ppm
Adverse Effects
Lachrymator
Yes
Toxic Pneumonitis
Yes
Dermatotoxin
Skin burns
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: