Diacetone alcohol
Agent Name
Diacetone alcohol
Alternative Name
4-Hydroxy-4-methyl-2-pentanone
CAS Number
123-42-2
Formula
C6-H12-O2
Major Category
Solvents
Synonyms
4-Hydroxy-4-methyl-2-pentanone; 2-Methyl-2-pentanol-4-one; 2-Pentanone, 4-hydroxy-4-methyl-; 4-Hydroxy-2-keto-4-methylpentane; 4-Hydroxy-4-methyl pentan-2-one; 4-Hydroxy-4-methylpentanone-2; Acetonyldimethylcarbinol; Diacetone; Diacetone alcohol; Diacetonyl alcohol; Diketone alcohol; Dimethyl acetonyl carbinol; Pyranton; Pyranton A; Tyranton; [ChemIDplus] UN1148
Category
Other Solvents
Description
Colorless liquid with a faint, minty odor; [NIOSH]
Sources/Uses
Used in antifreeze and brake fluids; also used as a solvent to make nitrocellulose, cellulose acetate, celluloid, pigments, waxes, and oils; [ACGIH]
Comments
Narcosis induced in animal inhalation studies; [ACGIH]
Biomedical References
Exposure Assessment
Skin Designation (ACGIH)
Insufficient data
TLV (ACGIH)
50 ppm
PEL (OSHA)
50 ppm
MAK
20 ppm
IDLH (NIOSH)
1800 ppm
Excerpts from Documentation for IDLHs
It has been reported that eye irritation appeared in volunteers exposed for 15 minutes at 100 ppm [Silverman et al. 1946].
Vapor Pressure
1.71 mm Hg
Odor Threshold Low
0.27 ppm
Odor Threshold High
1.1 ppm
Lethal Concentration
LCLo (rat) = 1,000 ppm/4h
Explanatory Notes
IDLH = 10% LEL (lower explosive limit); Detection odor threshold from AIHA (mean = 0.27 ppm); Flash point = 66 deg C; VP = 0.97 MM HG at 20 deg C; {HSDB]
NFPA
high ambient temp required
Adverse Effects
Neurotoxin
Acute solvent syndrome
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: