Diisobutyl ketone
Agent Name
Diisobutyl ketone
Alternative Name
2,6-Dimethyl-4-heptanone
CAS Number
108-83-8
Formula
C9-H18-O
Major Category
Solvents
Synonyms
2,6-Dimethyl-4-heptanone (natural);2,6-Dimethylheptan-4-one; 2,6-Dimethylheptanone; 4-Heptanone, 2,6-dimethyl-; DIBK; Diisobutyl ketone; Isobutyl ketone; Isovalerone; Valerone; s-Diisopropylacetone; sec-Diisopropyl acetone; sym-Diisopropylacetone; [ChemIDplus] UN1157
Category
Ketones (<C12)
Description
Colorless liquid with a mild, sweet odor; [NIOSH]
Sources/Uses
"Mainly used as coating solvent"; [HSDB]
Comments
Humans experience offensive irritating effects below concentrations that cause CNS depression in experimental animals. [HSDB]
Biomedical References
Exposure Assessment
Skin Designation (ACGIH)
Insufficient data
TLV (ACGIH)
25 ppm
PEL (OSHA)
50 ppm
IDLH (NIOSH)
500 ppm
Excerpts from Documentation for IDLHs
Human data: It has been reported that a 3hour exposure at 50 or 100 ppm caused slight irritation to the eyes, nose, and throat [Smyth et al. 1949].
Vapor Pressure
1.65 mm Hg
Odor Threshold Low
0.11 ppm
Odor Threshold High
0.31 ppm
Lethal Concentration
LCLo (rat) = 2,000 ppm/4H
Explanatory Notes
Odor threshold (detection at 0.11 ppm and recognition at 0.31 ppm) from CHEMINFO; Flash point = 49 deg C; VP from HSDB;
NFPA
high ambient temp required
Adverse Effects
Neurotoxin
Acute solvent syndrome
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: