Trifluoromethanesulfonic acid
Agent Name
Trifluoromethanesulfonic acid
CAS Number
1493-13-6
Formula
C-H-F3-O3-S
Major Category
Other Classes
Synonyms
Methanesulfonic acid, trifluoro-; Perfluoromethanesulfonic acid; Methanesulfonic acid, 1,1,1-trifluoro-; [ChemIDplus] Triflic acid; TFMSA; [Merck Index] UN3265
Category
Organic Acids
Description
Colorless hygroscopic liquid; [Merck Index]
Sources/Uses
Used as a catalyst, solvent for ESR, acid titrant, and with trifluoroacetic acid in peptide synthesis; [Merck Index]
Comments
Highly corrosive to skin; [Quick CPC] "One of the strongest acids known." May cause burns; [Merck Index] Oral LD50 (rat) is between 500 and 2,000 mg/kg; An acute dermal toxicity study of rats at 2,000 mg/kg produced extensive and severe local skin effects considered to be life threatening; 50 mg/kg doses were tolerated and showed no significant adverse effects at necropsy; No evidence of skin sensitization in guinea pigs; No evidence of mutagenicity; [EPA TSCA] Causes burns; Inhalation of high concentration can cause chemical pneumonitis; [Alfa Aesar MSDS]
Biomedical References
Exposure Assessment
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Corrosive liquid, acidic, organic, n.o.s."
Adverse Effects
Toxic Pneumonitis
Yes
Dermatotoxin
Skin burns
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.