Methane sulfonyl chloride

Synonyms

Methanesulfonyl chloride; Chloro methyl sulfone; Chloromethyl sulfone; Mesyl chloride; Methanesulfonic acid chloride; Methanesulfuryl chloride; Methanesulphonyl chloride; Methyl sulfochloride; Methyl sulfonyl chloride; Methylsulfonyl chloride; [ChemIDplus] MSC; [IUCLID] UN3246

Category

Acid Halides

Description

Colorless to pale yellow, fuming liquid; [ICSC] Unpleasant odor; [HSDB]

Sources/Uses

Used as an intermediate in the production of drugs, flame retardants, and other chemicals; Also used as a stabilizer, catalyst, curing agent, and chlorinating agent; Has been detected in air samples at a pulp mill that used chlorine-containing bleaching agents; [HSDB]

Comments

Highly corrosive to skin; [Quick CPC] It is "tear drawing" and corrosive to the skin and respiratory tract; [ICSC] May form hydrogen chloride gas on contact with water or moisture, although experiments at Argonne National Laboratory have shown essentially no reaction with water; Highly toxic by ingestion, inhalation, and skin absorption; [CAMEO] Slowly hydrolyzed by water forming hydrochloric acid; A lachrymator; Corrosive to tissue; [EPA OHM/TADS] Hydrolyzed by water evolving acidic gas; Causes burns; Inhalation may cause corrosive injuries to upper respiratory tract and lungs; Highly toxic by ingestion, inhalation, and skin absorption; [Aldrich MSDS]

Biomedical References

Yes

3.09 mm Hg

LCLo = 620 mg/m3/6hr

Explanatory Notes

VP from HSDB; LC50 (rat) = 25 ppm/4hr; 200 ppm/1hr; [HSDB]

Reference Link #2

Yes

Yes

Skin burns

Diseases

Occupational diseases associated with exposure to this agent:

• Pneumonitis, toxic

Processes

Industrial Processes with risk of exposure:

• Plastic Composites Manufacturing
• Pulp and Paper Processing