Hexamethylene diisocyanate homopolymer

Agent Name
Hexamethylene diisocyanate homopolymer
CAS Number
28182-81-2
Formula
(C8-H12-N2-O2)x-
Major Category
Plastics & Rubber
Synonyms
1,6-Diisocyanatohexane homopolymer; Hexamethylene diisocyanate polymer; Hexamethylene diisocyanate trimer; Hexamethylene diisocyanate, homopolymer; Hexamethylene isocyanate polymer; Poly(hexamethylene diisocyanate); Hexane, 1,6-diisocyanato-, homopolymer; Isocyanic acid, hexamethylene ester, polymers; [ChemIDplus] DESMODUR N 3400; 1,6-Hexamethylene Diisocyanate Based Polyisocyanate; [Bayer Material Science MSDS]
Category
Polymers
Description
Clear light yellow liquid; Nearly odorless; [Bayer Material Science MSDS]
Sources/Uses
Used as an industrial coating; [REPROTOX]
Comments
Contains 0.1-0.5% hexamethylene-1,6-diisocyanate (CAS# 822-06-0); Slowly reacts with water evolving carbon dioxide; An irritant that may cause transient corneal injury; May cause skin and respiratory sensitization; Inhalation of high concentrations may cause pulmonary edema; Chronic inhalation overexposure may cause lung injury including fibrosis and decreased function; [Bayer Material Science MSDS] See "Hexamethylene diisocyanate."
Biomedical References
Search PubMed

Exposure Assessment

Vapor Pressure
1.8E-05 mm Hg
Lethal Concentration
LC50 (rat) = 18,500 mg/m3/1hr
Explanatory Notes
LC50 (rat) = 158 mg/m3/4hr; [Bayer Material Science MSDS]

Adverse Effects

Skin Sensitizer
Yes
Asthma
Yes
Fibrogenic
Yes

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: