3-(Methylthio)propionaldehyde

Synonyms

3-(Methylmercapto)propionaldehyde; 3-(Methylthio)propanal; 3-Methylmercaptopropyl aldehyde; Methional; Methional (natural); Methylmercaptopropionic aldehyde; Propanal, 3-(methylthio)-; Propionaldehyde, 3-(methylthio)-; beta-(Methylmercapto)propionaldehyde; beta-(Methylthio)propionaldehyde; 4-Thiapentanal; [ChemIDplus] beta-(Methylthio)propionic aldehyde; Methyl mercaptopropionaldehyde; Thia-4-pentanal; Thiapentanal; [CAMEO] MTPA; MMP; [OECD SIDS: 3-(Methylthio) propionaldehyde - 2003] 3-MTP; [RTECS] UN2785

Category

Aldehydes

Description

Colorless liquid with a pungent odor; [ICSC] Colorless to amber liquid with an extremely bad and persistent odor; [CAMEO]

Sources/Uses

Naturally present in plants and aquatic animals; Used nearly exclusively as an intermediate in chemical synthesis; Also used in small quantities as a flavoring agent; [OECD SIDS: 3-(Methylthio) propionaldehyde - 2003]

Comments

Causes skin irritation and permanent injury to eyes in studies of rabbits; Shows skin sensitizing potential in guinea pig maximization tests; Mild hemolytic effects (reduced red blood cell counts and hemoglobin levels, increased blood bilirubin levels, and signs of increased hematopoiesis in the spleen) observed in 28-day oral study of rats; No evidence of adverse effects to male or female gonads or developmental toxicity in rats; [OECD SIDS: 3-(Methylthio) propionaldehyde - 2003] A severe skin, eye, and respiratory tract irritant; May cause skin sensitization; [ICSC] May cause mild irritation; [CAMEO] Safe when used as a flavoring agent in food; [JECFA] An irritant; Harmful by ingestion and inhalation; [Alfa Aesar MSDS]

Biomedical References

0.75 mm Hg

8E-05 ppm

LC50 (rat) = 5,820 mg/m3/4hr

high ambient temp required

Yes

Diseases

Occupational diseases associated with exposure to this agent:

• Contact dermatitis, allergic