Methyltrichlorosilane
Agent Name
Methyltrichlorosilane
CAS Number
75-79-6
Formula
C-H3-Cl3-Si
Major Category
Toxic Gases & Vapors
Synonyms
Methyl-trichlorsilan [Czech]; Methylsilicochloroform; Methylsilyl trichloride; Monomethyltrichlorosilane; Silane, methyltrichloro-; Silane, trichloromethyl-; Trichlor-methylsilan [Czech]; Trichloromethylsilane; Trichloromethylsilicon; UN1250; [ChemIDplus]
Category
Chlorosilanes
Description
Colorless liquid with a sharp, irritating odor; [CHRIS]
Sources/Uses
Used as a chemical intermediate for silicones; [Hawley]
Comments
Liquid may cause second or third degree burns after brief skin contact. [CHRIS] Reacts violently with water to release hydrogen chloride; Inhalation can cause acute pulmonary edema; [ICSC] Toxicity is due to HCl, which is released when methytrichlorosilane contacts moisture; [AIHA]
Biomedical References
Exposure Assessment
TIH
Yes
Dangerous When Wet
Yes
Vapor Pressure
167 mm Hg
Lethal Concentration
LC50 (rat) = 450 ppm/4H
Explanatory Notes
Not TIH in land-based spills, but TiH substance released when spilled in water; [ERG 2016] VP from ChemIDplus;
NFPA
may ignite at ambient temp
ERPG-1
0.5 ppm
ERPG-2
3 ppm
ERPG-3
15 ppm
WEEL
Ceiling = 1 ppm
Adverse Effects
Lachrymator
Yes
Toxic Pneumonitis
Yes
Dermatotoxin
Skin burns
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: