Nerol

Synonyms

(Z)-Geraniol; 2,6-Octadien-1-ol, 3,7-dimethyl-, (Z)-; 2-cis-3,7-Dimethyl-2,6-octadien-1-ol; 3,7-Dimethyl-2,6-octadien-1-ol, (Z)-; 3,7-Dimethyl-2,6-octadien-1-ol, cis-; Nerol (natural); Nerol 900; Neryl alcohol; cis-Geraniol; 2,6-Octadien-1-ol, 3,7-dimethyl-, (2Z)-; [ChemIDplus]

Category

Plant Oils and Extracts

Description

Liquid with an odor of sweet rose; [Merck Index] Colorless to pale yellow liquid with a pleasant odor; [CAMEO]

Sources/Uses

Permitted for use as an inert ingredient in non-food pesticide products; [EPA] Present in many essential oils; Used as a base for perfume manufacture; [Merck Index] Also used as a flavoring agent; [CAMEO] The cis-isomer of geraniol; [Merck Index]

Comments

Causes respiratory depression in acute inhalation studies of mice; Causes general anesthesia in oral lethal-dose studies of rats; [RTECS] Mortality, stomach lesions, and cytoplasmic vacuolization (lipidosis) of the liver, kidney, and myocardium in 13-week oral study of mice (LOAEL of 2,000 mg/kg/day); [EPA ChAMP: Terpenoid Primary Alcohols and Related Esters - 2009] Safe when used as a flavoring agent in food; [JECFA] A maximization study of 25 volunteers showed no skin sensitization at 4% in petrolatum; [IUCLID] A skin and strong eye irritant; [Sigma-Aldrich MSDS] See "Geraniol."

Biomedical References

0.03 mm Hg

must be preheated

Acute solvent syndrome

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases

Occupational diseases associated with exposure to this agent:

• Solvents, acute toxic effect