n-Butyl isocyanate
Agent Name
n-Butyl isocyanate
CAS Number
111-36-4
Formula
C5-H9-N-O
Major Category
Toxic Gases & Vapors
Synonyms
1-Isocyanatobutane; BIC; Butane, 1-isocyanato-; Butyl isocyanate; Isocyanic acid, butyl ester; UN2485; [ChemIDplus]
Category
Monoisocyanates
Description
Colorless liquid;
Sources/Uses
Used as a chemical intermediate in the production of insecticides, fungicides, and pharmaceuticals (sulfonylureas for diabetes); [HSDB]
Comments
A lachrymator; The liquid can cause severe skin irritation and permanent eye damage. Liquid causes skin burns in animal experiments; An strong irritant by inhalation similar to methyl isocyanate; [CHEMINFO]
Biomedical References
Exposure Assessment
TIH
Yes
Vapor Pressure
17.6 mm Hg
Lethal Concentration
LC50 (rat) = 3,000 mg/m3
Explanatory Notes
VP from ChemIDplus;
NFPA
may ignite at ambient temp
ERPG-1
0.01 ppm
ERPG-2
0.05 ppm
ERPG-3
1 ppm
Adverse Effects
Lachrymator
Yes
Toxic Pneumonitis
Yes
Dermatotoxin
Skin burns
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent: