Thiamine

Agent Name
Thiamine
Alternative Name
Vitamin B1
CAS Number
59-43-8
Formula
C12-H17-N4-O-S.Cl
Major Category
Biological Agents
Thiamine formula graphical representation
Synonyms
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methylthiazolium chloride; Aneurine; Apatate Drape; B-Amin; Beivon; Betabion; Bethiamin; Oryzanin; Oryzanine; Thiacoat; Thiamin; Thiamine monochloride; Thiamine, chloride; Thiaminum [INN-Latin]; Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl- chloride; Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl-chloride; Tiamina [INN-Spanish]; Vitamin B1; Vitaneurin; [ChemIDplus]
Category
Vitamins and Derivatives
Description
Solid with a slight odor; [HSDB] Crystals; [Avocado Research MSDS]
Sources/Uses
An essential vitamin for carbohydrate metabolism and nerve function; Found in whole grains, meats, vegetables, milk, legumes, fruit, rice husks, and yeast; [Merck Index] Used as a nutritional supplement and flavoring agent for foods; [FDA] Used as a medicine, nutrient, in enriched flours, and other foods; [HSDB]
Comments
A water-soluble vitamin used to treat beriberi and Wernicke-Korsakoff syndrome; Anaphylactoid reactions were reported after intravenous injection--rare with new preparations; [Olson, p. 628] Hydrochloride: Safe when used as a flavoring agent in food; [JECFA] Occupational asthma confirmed with broncho-provocation testing in a worker manufacturing cereal; [Malo]
Biomedical References

Exposure Assessment

Vapor Pressure
1.8E-10 mm Hg

Adverse Effects

Asthma
Yes

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent: