Tetrahydrofolic acid

Synonyms

5,6,7,8-Tetrahydrofolic acid; Tetrahydrofolate; Tetrahydropteroylglutamic acid; Glutamic acid, N-(p-(((2-amino-3,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-, L-; N-(4-(((2-Amino-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid; [ChemIDplus] 5,6,7,8-Tetrahydropteroyl-L-glutamic acid; [Sigma-Aldrich MSDS]

Category

Vitamins and Derivatives

Description

Powder; [Sigma-Aldrich MSDS]

Sources/Uses

"Tetrahydrofolic acid, or tetrahydrofolate, is a folic acid derivative." [Wikipedia]

Comments

Causes changes in liver weights, normocytic anemia, changes in renal tubules, weight loss, and effects on transaminases in acute subcutaneous studies of rats; [RTECS] May cause irritation; [Sigma-Aldrich MSDS] See "Folic acid."

Biomedical References

Occupational hepatotoxin (principal effect)

Diseases

Occupational diseases associated with exposure to this agent:

• Hepatitis, chemical