Calcitriol
Agent Name
Calcitriol
CAS Number
32222-06-3
Formula
C27-H44-O3
Major Category
Biological Agents
Synonyms
(5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1alpha,3beta,25-triol; 1,25-(OH)2D3; 1,25-DHCC; 1,25-Dihydroxycholecaliferol; 1,25-Dihydroxyvitamin D; 1-alpha,25-Dihydroxycholecalciferol; 1-alpha,25-Dihydroxyvitamin D3; 1alpha,25-Dihydroxycholecalciferol; 1alpha,25-Dihydroxyvitamin D; 9,10-Seco(5Z,7E)-5,7,10(19)-cholestatriene-1alpha,3beta,25-triol; Calcijex; Calcitriolum [INN-Latin]; DN 101; DN-101; Dihydroxyvitamin D3; Ro 21-5535; Ro 215535; Rocaltrol; Soltriol; Topitriol; U 49562; Vectical; 9,10-Secocholesta-5,7,10(19)-triene-1,3,25-triol, (1alpha,3beta,5Z,7E)-; Cholecalciferol, 1-alpha,25-dihydroxy-; [ChemIDplus] UN2811
Category
Vitamins and Derivatives
Description
White solid; [Merck Index]
Sources/Uses
Active form of vitamin D3 used therapeutically (calcium regulator, vitamin, antihyperparathyroid, antineoplastic, and antipsoriatic); [Merck Index] "Calcitriol, also called 1,25-dihydroxycholecalciferol or 1,25-dihydroxyvitamin D3, is the hormonally active form of vitamin D with three hydroxyl groups (abbreviated 1,25-(OH)2D3 or simply 1,25(OH)2D), . . " [Wikipedia]
Comments
May cause irritation; Highly toxic by ingestion; Toxic by inhalation; Targets the gastrointestinal tract, bone, kidney, and CNS; Suspected of causing toxicity to human reproduction; [Sigma-Aldrich MSDS] See "Vitamin D."
Biomedical References
Exposure Assessment
Vapor Pressure
1.2E-12 mm Hg
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Toxic solid, organic, n.o.s."
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.