(R,R)-Jacobsen's catalyst

Agent Name
(R,R)-Jacobsen's catalyst
CAS Number
138124-32-0
Formula
C36-H52-Cl-Mn-N2-O2
Major Category
Metals
Synonyms
(R,R)-(N,N'-Bis(3,5-di-tert-butyl-salicylidene)-1,2-cyclohexanediamine)manganese(III) chloride; [Merck Index] (R,R)-(-)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminomanganese(III) chloride; Jacobsen's catalyst; [Sigma-Aldrich MSDS]
Category
Manganese Compounds, Inorganic
Description
Dark brown powder; [Sigma-Aldrich MSDS]
Sources/Uses
Used as a chiral catalyst for the epoxidation of olefins; [Merck Index]
Comments
A skin and strong eye irritant; [Sigma-Aldrich MSDS] See "Manganese" and the linked occupational diseases.
Biomedical References
Search PubMed

Exposure Assessment

TLV (ACGIH)
0.02 mg/m3, as Mn (respirable fraction), 0.1 mg/m3, as Mn (inhalable fraction)
PEL (OSHA)
Ceiling(OSHA) = 5 mg/m3, as Mn
MAK
0.2 mg/m3, as Mn (inhalable fraction), 0.02 mg/m3, as Mn (respirable fraction)

Adverse Effects

Neurotoxin
Parkinsonism

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent: