1,1-Difluoro-1,2,2-trichloroethane
Agent Name
1,1-Difluoro-1,2,2-trichloroethane
Alternative Name
HCFC-122
CAS Number
354-21-2
Formula
C2-H-Cl3-F2
Major Category
Solvents
Synonyms
1,1,2-Trichloro-2,2-difluoroethane; 1,2,2-Trichloro-1,1-difluoroethane; F 122 (halocarbon); FC 122; Freon 122; Frigen 122; HCFC 122; HCFC-122; R 122; Ucon fluorocarbon 122; Ethane, 1,1-difluoro-1,2,2-trichloro-; Ethane, 1,2,2-trichloro-1,1-difluoro-; Difluorotrichloroethane; [ChemIDplus] UN3082
Category
Chlorofluorocarbons
Description
Colorless liquid; [Alfa Aesar MSDS]
Comments
A mild to severe skin irritant; Causes somnolence and ataxia in oral lethal-dose studies of rats; Cause estrogenic effects, weight loss, fatty liver degeneration, other liver changes, changes in liver weight, and effects on hepatic microsomal mixed oxidase in 90-day intermittent inhalation studies of rats; [RTECS] May cause skin and eye irritation; [Alfa Aesar MSDS] See "1,1,1-Trifluoro-2,2-dichloroethane."
Biomedical References
Exposure Assessment
Lethal Concentration
LCLo (rat) = 4,000 ppm/4hr
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Environmentally hazardous substances, liquid, n.o.s."
Adverse Effects
Neurotoxin
Acute solvent syndrome
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent: