1-Naphthylisothiocyanate

Agent Name
1-Naphthylisothiocyanate
CAS Number
551-06-4
Formula
C11-H7-N-S
Major Category
Nitrogen Compounds
1-Naphthylisothiocyanate formula graphical representation
Synonyms
1-Isothiocyanate-naphthalene; 1-Isothiocyanatonaphthalene; 1-Naftylisothiokyanat [Czech]; 1-Naphthyl isothiocyanate; alpha-Naphthyl isothiocyanate; ANI; ANIT; Kesscocide; Naphthalene, isothiocyanato-; Isothiocyanic acid, 1-naphthyl ester; Naphthalene, 1-isothiocyanato-; [ChemIDplus] alpha-Naphthyl mustard oil; alpha-Naphthylisothiocyanate; Isothiocyanatonaphthalene; 1-Naphthyl ester isothiocyanic acid; [CAMEO] UN2811
Category
Isothiocyanates
Description
White nearly odorless solid; [Merck Index] Slightly yellow odorless powder; [Acros Organics MSDS]
Sources/Uses
"A tool for the study of liver damage which causes bile stasis and hyperbilirubinemia acutely and bile duct hyperplasia and biliary cirrhosis chronically, with changes in hepatocyte function. It may cause skin and kidney damage." [ChemIDplus] Has been used as an insecticide (with pyrethrum); [NTP]
Comments
Causes abnormal liver function tests, cholestatic jaundice, and hepatitis in acute oral studies of rats; [RTECS] A hepatotoxin; [Merck Index] Slowly hydrolyzed by water; [CAMEO] May cause liver and kidney injury; [NTP] May cause irritation; Harmful by ingestion; May cause liver injury; [Acros Organics MSDS] See "Phenyl isothiocyanate."
Biomedical References

Exposure Assessment

Vapor Pressure
0.000132 mm Hg
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Toxic solid, organic, n.o.s."

Adverse Effects

Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Diseases, Processes, and Activities Linked to This Agent

Processes

Industrial Processes with risk of exposure: