2,4,6-Tri-tert-butylphenol
Agent Name
2,4,6-Tri-tert-butylphenol
Alternative Name
2,4,6-Tris(1,1-dimethylethyl)phenol
CAS Number
732-26-3
Formula
C18-H30-O
Major Category
Other Classes
Synonyms
2,4,6-Tri-t-butylphenol; 2,4,6-Tri-tert-butyl-1-hydroxybenzene; 2,4,6-Tris(tert-butyl)phenol; Alkofen B; P 23; P23; TM02; 2,4,6-Tris(1,1-dimethylethyl)phenol; Phenol, 2,4,6-tri-tert-butyl- (6CI,7CI,8CI); Phenol, 2,4,6-tris(1,1-dimethylethyl)-; Phenol, 2,4,6-tri-tert-butyl-; [ChemIDplus] TBP; [HSDB] UN3077
Category
Phenols
Description
Solid; [HSDB] Yellow crystalline solid; [Sigma-Aldrich MSDS]
Sources/Uses
Used in Canada as an antioxidant in hydrocarbon fuels (gasoline, jet fuel, diesel, and biodiesel) and formerly as a lubricant additive; [ExPub: Government of Canada: Proposed Risk Management Approach] Also used as a starting material for 2,6-di-tert-butyl-4-methoxyphenol (antioxidant); [HSDB] Used as an intermediate; [ExPub: ECHA REACH Registrations]
Comments
Di- and tri-substituted mixed alkylphenols: Category members demonstrate moderate skin irritation; Low acute oral and moderate acute dermal toxicity; Evidence of liver toxicity in repeated-dose oral studies of rats; Developmental toxicity at doses producing marginal systemic toxicity in adults; No evidence of reproductive toxicity, mutagenicity, or carcinogenicity; [EPA ChAMP: Hazard Characterization] May cause irritation; Harmful by ingestion; [Sigma-Aldrich MSDS]
Biomedical References
Exposure Assessment
Vapor Pressure
0.000661 mm Hg
Explanatory Notes
The Guide in the Emergency Response Guidebook is for "Environmentally hazardous substances, solid, n.o.s."
Adverse Effects
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.