2-Methyl-6-nitroaniline

Synonyms

1-Amino-2-methyl-6-nitrobenzene; 2-Methyl-6-nitro-benzenamine; 6-Nitro-o-toluidine; Benzenamine, 2-methyl-6-nitro-; [ChemIDplus] 2-Amino-3-methylnitrobenzene; 2-Amino-3-nitrotoluene; 6-Methyl-2-nitroaniline; 3-Nitro-2-aminotoluene; 2-Nitro-6-methylaniline; o-Toluidine, 6-nitro-; [CAMEO] 2-Methyl-6-nitrophenylamine; 3-Nitro-2-amino-toluene; 3-Nitro-2-amino-toluol; 3-Nitro-2-toluidine; [EC: SCCNFP] UN2660

Category

Nitroanilines

Description

Orange-yellow or brown solid; [CAMEO] Dark red solid; [EC: SCCNFP] Dark red crystalline solid; [Sigma-Aldrich MSDS]

Sources/Uses

Used in semi-permanent hair dyes; [EC: SCCNFP]

Comments

A mild skin and eye irritant in rabbits at 3% concentration in 1,2-propanediol; No evidence of skin sensitization in guinea pigs; Hepatotoxicity observed in 28-day oral studies of rats; No evidence of embryotoxicity or teratogenicity in rats; [EC: SCCNFP] May cause irritation; May induce methemoglobinemia; Toxic by ingestion, inhalation, and skin absorption; Targets the blood; [Sigma-Aldrich MSDS] See "2-Nitroaniline."

Biomedical References

Explanatory Notes

The Guide in the Emergency Response Guidebook is for "Nitrotoluidines (mono)."

MetHgb is secondary toxic effect

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Processes

Industrial Processes with risk of exposure:

• Dressing Hair