Urethane

Synonyms

Carbamic acid, ethyl ester; A 11032; Aethylcarbamat [German]; Aethylurethan [German]; Carbamidsaeure-aethylester [German]; Estane 5703; Ethyl carbamate; Ethyl urethan; Ethyl urethane; Ethylcarbamate; Ethylester kyseliny karbaminove [Czech]; Ethylurethan; Ethylurethane; Leucethane; O-Ethylurethane; Pracarbamin; Pracarbamine; U-Compound; Uretan etylowy [Polish]; Uretano [DCIT]; Urethan; Urethanum [INN-Latin]; X 41; Carbamic acid, ethyl ester; [ChemIDplus]

Category

Carbamic Acid Esters

Description

Water-soluble crystals or white powder; [CAMEO]

Sources/Uses

Used as an antineoplastic agent, veterinary anesthetic, and chemical intermediate; [ChemIDplus] Used as an intermediate, amino resin modifier, solvent, and animal anesthetic; Occurs naturally in fermented wines and foods; [Merck Index]

Comments

Harmful by inhalation or skin absorption and toxic by ingestion; Toxic to the liver; May cause CNS depression; [CAMEO] Inhalation can cause unconsciousness; [ICSC] Induces genetic damage in germ cells of humans or animals (3A); [MAK]

Biomedical References

0.36 mm Hg

Explanatory Notes

mp = 118-122 deg F; bp = 360-363 deg F at 760 mm Hg; VP = 5.0 mm Hg at 150.4 deg F; [CAMEO] VP = 48 Pa (0.36 mm Hg) at 25 deg C; [ICSC]

Acute solvent syndrome

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Yes

Probable (2a)

Anticipated human carcinogen

Diseases

Occupational diseases associated with exposure to this agent:

• Solvents, acute toxic effect