Bis(triphenylphosphine)nickel(II) chloride

Synonyms

Bis(triphenylphosphine)dichloronickel; Bis(triphenylphosphine)nickel dichloride; Dichlorobis(triphenylphosphine)nickel; Nickel, bis(triphenylphosphine)dichloro-; Nickel, dichlorobis(triphenylphosphine)-; Phosphine, tributyl-, compd. with nickelchloride (2:1); [ChemIDplus]

Category

Metals, Organic Compounds

Description

Solid; [Sigma-Aldrich MSDS]

Sources/Uses

Used as a solvent in the production of active pharmaceutical ingredients (API); [ECHA REACH Registrations]

Comments

Intravenous LD50 (mouse) = 56 mg/kg; [RTECS] May cause skin sensitization; [ECHA REACH Registrations] May cause skin sensitization; Possible carcinogen; [Sigma-Aldrich MSDS] See "Nickel" and linked occupational diseases.

Biomedical References

1 mg/m3, as Ni

Yes

Yes

Established

Human carcinogen

Diseases

Occupational diseases associated with exposure to this agent:

• Asthma, occupational
• Contact dermatitis, allergic