Isopropylamine

Agent Name
Isopropylamine
CAS Number
75-31-0
Formula
C3-H9-N
Major Category
Nitrogen Compounds
Isopropylamine formula graphical representation
Synonyms
1-Methylethylamine; 2-Amino-propaan [Dutch]; 2-Amino-propano [Italian]; 2-Aminopropan [German]; 2-Aminopropane; 2-Propanamine; 2-Propaneamine; 2-Propylamine; Isopropilamina [Italian]; Monoisopropylamine; Propanal, 2-amino-; Propane, 2-amino-; sec-Propylamine; [ChemIDplus] UN1221
Category
Amines, Aliphatic
Description
Colorless liquid with an ammonia-like odor; Note: A gas above 91 degrees F; [NIOSH]
Sources/Uses
Used as a solvent and as an intermediate in the synthesis of dyes, rubber additives, pesticides, surface active agents, and pharmaceuticals; Generated from plant and animal waste decomposition; [ACGIH]
Comments
Liquid causes first degree burns on short exposure. [CHRIS] Corrosive to skin; [Quick CPC] TLV Basis is irritation of upper respiratory tract and eye (visual impairment). [ACGIH] May cause permanent eye injury; Transient visual effects ("blue haze" or "halo vision") occur at low concentrations; [CHEMINFO]
Biomedical References

Exposure Assessment

Skin Designation (ACGIH)
Yes
TLV (ACGIH)
2 ppm
STEL (ACGIH)
10 ppm
PEL (OSHA)
5 ppm
MAK
5 ppm, Ceiling = 10 ppm
IDLH (NIOSH)
750 ppm
Excerpts from Documentation for IDLHs
Other animal data: It has been reported that rats have survived an exposure to 4,000 ppm for 4 hours [Smyth et al. 1951]. Human data: Volunteers have complained of nose and throat irritation after brief exposures to concentrations ranging from 10 to 20 ppm [Amoore and Hautala 1983].
Vapor Pressure
579.6 mm Hg
Odor Threshold Low
0.21 ppm
Odor Threshold High
0.7 ppm
Lethal Concentration
LC50 (rat) = 4,000 ppm/4H
Explanatory Notes
Detection odor threshold from AIHA (mean = 0.21 ppm); Flash point = -26 deg C; VP from HSDB;
Reference Link #2
NFPA
burn readily

Adverse Effects

Toxic Pneumonitis
Yes
Dermatotoxin
Skin burns

Diseases, Processes, and Activities Linked to This Agent

Other Information
No other related information on this agent was found.