Aldrin
Agent Name
Aldrin
CAS Number
309-00-2
Formula
C12-H8-Cl6
Major Category
Pesticides
Synonyms
1,2,3,4,10,10-Hexachloro-1,4,4a,5,8,8a-hexahydro-endo-1,4-exo-5,8-dimethanonaphthalene; HHDN; Octalene; [NIOSH]
Category
Organochlorine Pesticides
Description
Colorless to dark-brown crystalline solid with a mild chemical odor. [Note: Formerly used as an insecticide.] [NIOSH]
Sources/Uses
Used as an insecticide;
Comments
Not currently registered or used in the USA, Aldrin converts to dieldrin in the body and in the environment. High-dose animal studies show that organochlorine insecticides can cause liver injury. [LaDou, p. 593] "No evidence of hepatic injury in humans as the result of environmental contamination." [Zimmerman, p. 414] See ATSDR ToxProfiles.
Restricted
In 1974, EPA banned all uses except termite control. In 1987, EPA banned all uses. [ATSDR ToxFAQs]
Reference Link #1
Biomedical References
Exposure Assessment
Skin Designation (ACGIH)
Yes
Bioaccumulates
Yes
TLV (ACGIH)
0.05 mg/m3, inhalable fraction and vapor
PEL (OSHA)
0.25 mg/m3
MAK
0.25 mg/m3, inhalable fraction
IDLH (NIOSH)
25 mg/m3
Vapor Pressure
1.2E-05 mm Hg
Explanatory Notes
VP from HSDB;
Reference Link #2
Adverse Effects
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
IARC Carcinogen
Probable (2a)
ACGIH Carcinogen
Confirmed Animal
Other Poison
Organochlorine
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent: