Dibutyl phenyl phosphate
Agent Name
Dibutyl phenyl phosphate
CAS Number
2528-36-1
Formula
C14-H23-O4-P
Major Category
Other Classes
Synonyms
Butyl phenyl phosphate ((BuO)2(PhO)PO); Dibutyl phenyl phosphate; Phosphoric acid, dibutyl phenyl ester; Di(n-butyl) phenyl phosphate; [ChemIDplus]
Category
Organophosphates, Other
Description
Clear slightly yellow liquid; [HSDB] Very low solubility in water; [ACGIH]
Sources/Uses
Used as a hydraulic fluid in aircraft engines and as a plasticizer for polyvinyl chloride; [HSDB] Use in the USA is limited; Workers may be exposed during aircraft maintenance, but exposure levels have not been reported; [ACGIH]
Comments
Oral LD50 (rats) = 2620 mg/kg; Dermal LD50 (rabbits) = 5000 mg/kg; Reduces plasma cholinesterase activity and causes liver injury in high-dose animal studies; A skin, eye, and respiratory tract irritant; [ACGIH] An irritant; [MSDSonline]
Biomedical References
Exposure Assessment
BEI
Acetylcholinesterase activity in red blood cells = 70% of individual's baseline; Butylcholinesterase activity in serum or plasma = 60% of individual's baseline; Sample at end of shift; [TLVs and BEIs]
Skin Designation (ACGIH)
Yes
TLV (ACGIH)
0.3 ppm
Vapor Pressure
0.007 mm Hg
Lethal Concentration
LC (rat) > 7mg/m3
Explanatory Notes
Flash point = 177 deg C; [HSDB]
Adverse Effects
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.