1,2-Dibromo-3-chloropropane

Agent Name
1,2-Dibromo-3-chloropropane
Alternative Name
DBCP
CAS Number
96-12-8
Formula
C3-H5-Br2-Cl
Major Category
Pesticides
1,2-Dibromo-3-chloropropane formula graphical representation
Synonyms
Dibromochloropropane; DBCP; [NIOSH]
Category
Fumigants
Description
Dense yellow or amber liquid with a pungent odor at high concentrations. [pesticide] [Note: A solid below 43 degrees F.] [NIOSH]
Comments
Strong positive data for testicular damage in animals and decreased sperm counts, azoospermia, and hormonal changes in humans; [ATSDR Case Studies # 29] "Germ cell mutagens that have shown to increase the mutant frequency in the progeny of exposed mammals." [MAK]
Restricted
All uses except on pineapple plantations in Hawaii canceled in 1979; use on pineapples cancelled in 1985; See 29CFR1910.1044;
Biomedical References

Exposure Assessment

PEL (OSHA)
0.001 ppm
Vapor Pressure
0.8 mm Hg
Lethal Concentration
LC50 (rat) = 103 ppm/8H
Explanatory Notes
VP = 0.58 mm Hg at 20 deg C; [HSDB]
Half Life
Animal studies: 80% of absorbed dose eliminated within 24 hours; [TDR, p. 479]

Adverse Effects

Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Reproductive Toxin
Yes
IARC Carcinogen
Possible (2b)
NTP Carcinogen
Anticipated human carcinogen

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: