1,2,5,6,9,10-Hexabromocyclododecane

Synonyms

Cyclododecane, 1,2,5,6,9,10-hexabromo-; Hexabromocyclododecane; [ChemIDplus]

Category

Other Plasticizers

Description

Solid; [HSDB] Beige powder; [MSDSonline]

Sources/Uses

Used as a flame retardant in polystyrene foam and low-density polystyrene foam; Also used in high-impact polystyrene, styrene-acrylonitrile resins, adhesives, and coatings; [HSDB]

Comments

An estimated 100 to 999 workers are exposed to this chemical during manufacturing, processing, and use in the US. The product used in animal testing was hexabromocyclododecane (mixed isomers), also called "Firemaster 100." There were no deaths after a 24-hour application to 20-30% of the body surface area, so the dermal LD50 (rabbit) was >20 gm/kg. The same chemical was used in the inhalation study, and the animals exhibited slight dyspnea, but no deaths, after 4-hour exposures to visibly dusty conditions. The LC50 (rats) was >202 mg/L/4h. Testing for eye irritation was negative. [HSDB] May cause irritation; [MSDSonline]

Biomedical References

4.7E-07 mm Hg

LC50 (rat) > 202 mg/L/4h

Processes

Industrial Processes with risk of exposure:

• Plastic Composites Manufacturing
• Working with Glues and Adhesives