2-Aminopyridine
Agent Name
2-Aminopyridine
CAS Number
504-29-0
Formula
C5-H6-N2
Major Category
Nitrogen Compounds
Synonyms
2-Aminopyridine; alpha-Aminopyridine; 1,2-Dihydro-2-iminopyridine; 2-Aminopryidine; 2-Aminopyridine; 2-Pyridinamine; 2-Pyridylamine; Amino-2 pyridine; alpha-Aminopyridine; alpha-Pyridinamine; alpha-Pyridylamine; o-Aminopyridine; UN2671; [ChemIDplus]
Category
Pyridines
Description
White powder, leaflets, or crystals with a characteristic odor; [NIOSH]
Sources/Uses
Used to manufacture drugs and dyes; [Merck Index # 473]
Comments
A chemical plant worker died after a spill which contaminated his clothing. He did not remove his clothing, and symptoms began about 2 hours after the exposure with headache and dizziness followed by respiratory distress and convulsions. [ACGIH] See "Pyridine."
Biomedical References
Exposure Assessment
Skin Designation (ACGIH)
Insufficient data
TLV (ACGIH)
0.5 ppm
PEL (OSHA)
0.5 ppm
IDLH (NIOSH)
5 ppm
Excerpts from Documentation for IDLHs
Very little quantitative data are available on which to base an IDLH for 2-aminopyridine. The chosen IDLH is based on the statement by ACGIH [1971] that a 5-hour exposure to about 5 ppm produced headache, increased blood pressure, and nausea in a worker [Watrous and Schulz 1950].
Vapor Pressure
0.096 mm Hg
Explanatory Notes
Flash point = 198 deg F; [CAMEO]
Adverse Effects
Neurotoxin
Other CNS neurotoxin
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent: