2,3-Dichloropropanol

Synonyms

1,2-Dichloro-3-propanol; 1-Propanol, 2,3-dichloro-; 2,3-Dichloro-1-propanol; 2,3-Dichloropropyl alcohol; Glycerol 1,2-dichlorohydrin; Glycerol alpha,beta-dichlorohydrin; alpha,beta-Dichlorohydrin; 2,3-Dichloropropan-1-ol; [ChemIDplus] UN2750

Category

Halogenated Alcohols

Description

Colorless to amber liquid with an ethereal odor; [CAMEO]

Sources/Uses

Used for the production of epichlorohydrin; [HSDB]

Comments

Irritating to skin; Severely irritating to eyes; Poisonous by ingestion and skin contact; Moderately toxic by inhalation; "Two middle aged men developed severe hepatic injury just after cleaning a dichloropropanol tank at a plant producing dichloropropanol. They died from hepatic failure 4 and 11 days respectively, after carrying out the work. Liver specimens taken at autopsy from one of the cases showed submassive hepatic necrosis." [HSDB] Toxic after ingestion or skin absorption; An irritant; May cause serious injury to eyes; [MSDSonline]

Reference Link #1

Biomedical References

0.184 mm Hg

LCLo (rat) = 500 ppm/4h

Explanatory Notes

VP from ChemIDplus;

Reference Link #2

Occupational hepatotoxin (principal effect)

Diseases

Occupational diseases associated with exposure to this agent:

• Hepatitis, chemical