2-Octanone
Agent Name
2-Octanone
Alternative Name
Hexyl methyl ketone
CAS Number
111-13-7
Formula
C8-H16-O
Major Category
Solvents
Synonyms
Hexyl methyl ketone; 2-Octanone (natural); 2-Oxooctane; Methyl hexyl ketone; Methyl n-hexyl ketone; n-Hexyl methyl ketone; [ChemIDplus] Octan-2-one; [JECFA] UN1224
Category
Ketones (<C12)
Description
Colorless liquid with a pleasant odor; [Hawley]
Sources/Uses
Used in perfumes, flavorings, and odorants; Also used as a high-boiling solvent (especially for epoxy resin coatings); Also used in leather finishes and nitrocellulose lacquers; [Hawley] Used as a flavoring agent; [FDA]
Comments
May cause mild irritation; Inhalation of high concentrations can cause CNS depression; [HSDB] Safe when used as a flavoring agent in food; [JECFA] An irritant; Harmful by skin absorption; [Alfa Aesar MSDS]
Biomedical References
Exposure Assessment
Vapor Pressure
1.35 mm Hg
Odor Threshold Low
248 ppm
Lethal Concentration
LC50 (rat) > 2,132 ppm/6hr
Explanatory Notes
Odor threshold from HSDB; The Guide in the Emergency Response Guidebook is for "Ketones, liquid, n.o.s." VP from ChemIDplus;
NFPA
high ambient temp required
Adverse Effects
Neurotoxin
Acute solvent syndrome
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: