3-Picoline
Agent Name
3-Picoline
CAS Number
108-99-6
Formula
C6-H7-N
Major Category
Nitrogen Compounds
Synonyms
3-Methylpyridine; Pyridine, 3-methyl-; beta-Methylpyridine; beta-Picoline; m-Methylpyridine; m-Picoline; [ChemIDplus] UN2313
Category
Pyridines
Description
Colorless liquid with a sweet, but not unpleasant odor; [Merck Index]
Sources/Uses
Used as a solvent (pharmaceuticals, resins, and dyestuffs), rubber accelerator, laboratory reagent, and chemical intermediate; [HSDB] Picolines are constituents in cigarette smoke, bone oil, coal tar, and coke oven emissions. [AIHA] Used as a flavoring agent in foods and beverages; [IARC Monographs - 122]
Comments
A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation of high concentrations can cause unconsciousness; The liquid defats the skin; [ICSC] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; May be absorbed through skin; Causes CNS depression in high-dose animal studies; [MSDSonline] An irritant that can cause CNS depression; In one case, a worker exposed for 11 years had elevated liver enzymes; Liver changes occur in rats exposed to chronic high doses; [AIHA]
Biomedical References
Exposure Assessment
Vapor Pressure
6.05 mm Hg
Lethal Concentration
LCLo (rat) = 11,820 mg/m3/5h
Explanatory Notes
Flash point = 38 deg C; [ICSC] The Guide in the Emergency Response Guidebook is for "Picolines." VP from ChemIDplus;
NFPA
high ambient temp required
WEEL
2 ppm, STEL = 5 ppm
Adverse Effects
Neurotoxin
Other CNS neurotoxin
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Dermatotoxin
Skin burns
IARC Carcinogen
Possible (2b)
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.