Picramic acid

Synonyms

4,6-Dinitro-2-aminophenol; 1-Amino-2-hydroxy-3,5-dinitrobenzene; 2,4-Dinitro-6-aminophenol; 2-Amino-4,6-dinitrophenol; CI 76540; 6-Amino-2,4-dinitrophenol; Acide picramique [French]; C.I. Oxidation Base 21; CI Oxidation Base 21; Fourrine 4R; Fourrine 93; Furro 4R; Oxidation Base 21; Phenol, 2-amino-4,6-dinitro-; Zoba 4R; [ChemIDplus] UN3317

Category

Other Aromatics (Nitrogen)

Description

Dark red solid; [Merck Index]

Sources/Uses

Used as an explosive initiator, an oxidation base for dyeing fur, a component of electric detonation fuses, a reagent for albumin, an acid-base indicator, and in rinses for hair dyes and shampoos; Also used to make mordants and azo dyes; [HSDB]

Comments

Subcutaneous LDLo (rat) = 2100 mg/kg; [RTECS] Toxicity similar to that of 2,4-dinitrophenol; [Merck Index] Emergency treatment: "Dinitro phenol group"; [HSDB] Highly flammable and explosive; Desensitized by wetting; An irritant; Symptoms of poisoning include dizziness, abdominal cramps, vomiting, bloody diarrhea, weakness, and convulsions; [CAMEO] See "Dinitrophenol."

Biomedical References

4.16E-07 mm Hg

Explanatory Notes

Flash point = 210 deg C; [HSDB] The Guide in the Emergency Response Guidebook is for "2-Amino-4,6-Dinitrophenol, wetted with not less than 20% water."

MetHgb is secondary toxic effect

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Yes

Skin burns

Other Poison

Uncoupler

Diseases

Occupational diseases associated with exposure to this agent:

• Acute tubular necrosis
• Cataract, chemical or radiation induced
• Pentachlorophenol/Dinitrophenol, acute poisoning

Processes

Industrial Processes with risk of exposure:

• Dressing Hair
• Fur Dressing and Dyeing