tert-Butyl chromate

Agent Name
tert-Butyl chromate
CAS Number
1189-85-1
Formula
C8-H18-Cr-O4
Major Category
Metals
tert-Butyl chromate formula graphical representation
Synonyms
di-tert-Butyl ester of chromic acid; Bis (tert-butyl) chromate; t-Butyl chromate; [CHEMINFO]
Category
Metals, Organic Compounds
Description
Liquid; Note: Solidifies at 23-32 degrees F; [NIOSH]
Sources/Uses
Used to synthesize catalysts and other organic chemicals; also used as a curing agent for polyurethanes and polyolefins, e.g., polypropylene and polyethylene; [NIOSH Guidelines for Chemical Hazards]
Comments
Can cause acid-like burns; chronic exposure may result in kidney and liver damage; [NIOSH Guidelines for Chemical Hazards] May cause irritation of the skin, eyes, and respiratory tract; May have CNS effects, e.g., drowsiness; [CAMEO] Potential respiratory tract sensitizer; [CHEMINFO] See Chromium.
Biomedical References

Exposure Assessment

Skin Designation (ACGIH)
Yes
Bioaccumulates
Yes
Ceiling (ACGIH)
0.1 mg/m3, as CrO3
PEL (OSHA)
0.005 mg/m3, as CrO3
IDLH (NIOSH)
15 mg/m3, as Cr(VI)
Excerpts from Documentation for IDLHs
Very little toxicological data are available concerning the effects produced by exposure to tert­butyl chromate. Because AIHA [1965] reported that the severity of the health hazard is low for acute exposure to chromic acid, by analogy it is assumed that the hazard is also low for acute exposure to tert­butyl chromate. Therefore, the chosen IDLH is based on an analogy with chromic acid and chromates, which has an IDLH of 30 mg/m3 (as CrO3).

Adverse Effects

Skin Sensitizer
Yes
Asthma
Yes
Neurotoxin
Other CNS neurotoxin
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Nephrotoxin
Yes
Reproductive Toxin
Yes
Dermatotoxin
Skin burns

Diseases, Processes, and Activities Linked to This Agent

Diseases

Occupational diseases associated with exposure to this agent:

Processes

Industrial Processes with risk of exposure: