Caprolactam
Agent Name
Caprolactam
CAS Number
105-60-2
Formula
C6-H11-N-O
Major Category
Plastics & Rubber
Synonyms
1,6-Hexalactam; 1,6-Hexolactam; 1-Aza-2-cycloheptanone; 2-Azacycloheptanone; 2-Ketohexamethylenimine; 2-Oxohexamethyleneimine; 2-Oxohexamethylenimine; 2-Perhydroazepinone; 2H-Azepin-2-one, hexahydro-; 2H-Azepin-7-one, hexahydro-; 6-Aminocaproic acid lactam; 6-Aminohexanoic acid cyclic lactam; 6-Caprolactam; 6-Hexanelactam; A1030; Aminocaproic lactam; Caprolactam; Caprolactam monomer; Caprolattame [French]; Capron PK4; Cyclohexanone iso-oxime; Epsylon kaprolaktam [Polish]; Extrom 6N; Hexahydro-2-azepinone; Hexahydro-2H-azepin-2-one; Hexamethylenimine, 2-oxo-; Hexanoic acid, 6-amino-, cyclic lactam; Hexanoic acid, 6-amino-, lactam; Hexanolactam; Hexanone isoxime; Hexanonisoxim [German]; Kapromine; Stilon; e-Kaprolaktam [Czech]; epsilon-Caprolactam; [ChemIDplus] UN8027
Category
Other Monomers
Description
White, crystalline solid or flakes with an unpleasant odor; Note: Significant vapor concentrations would be expected only at elevated temperatures; [NIOSH]
Sources/Uses
Used as "a monomer for synthetic fibers, plastics, coatings, plasticizers, and paint vehicles and as a cross-linking agent for polyurethanes." [ACGIH]
Comments
May cause skin sensitization; A skin, eye, and respiratory tract irritant; Inhalation of high concentrations may cause CNS effects; [ICSC] Liver and kidney changes occur in subchronic animal studies using intraperitoneal doses. [ACGIH]
Reference Link #1
Biomedical References
Exposure Assessment
Skin Designation (ACGIH)
Insufficient data
TLV (ACGIH)
5 mg/m3, inhalable fraction and vapor
MAK
5 mg/m3, inhalable fraction
Vapor Pressure
0.0019 mm Hg
Lethal Concentration
LC50 (rat) = 300 mg/m3/2h
Explanatory Notes
Flash point = 110 deg C; VP from HSDB;
Reference Link #2
Adverse Effects
Skin Sensitizer
Yes
Neurotoxin
Other CNS neurotoxin
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
IARC Carcinogen
Not classifiable
ACGIH Carcinogen
Not Suspected
Diseases, Processes, and Activities Linked to This Agent
Diseases
Occupational diseases associated with exposure to this agent:
Processes
Industrial Processes with risk of exposure: