Captafol

Synonyms

Captofol; N-((1,1,2,2-Tetrachloroethyl)thio)-4-cyclohexene-1,2-dicarboximde; Crisfolatan; Difosan; Folcid; Haipen; Kenofol; Merpafol; Pillartan; Sanseal; Santar-SM; Sanspor; Difolatan

Category

Fungicides

Description

White, crystalline solid with a slight, characteristic pungent odor. [fungicide] [Note: Available commercially as a wettable powder or in liquid form.] [NIOSH]

Sources/Uses

The thiophthalimides are widely used fungicides on seeds, field crops, and stored produce; [EPA Pesticides] Used as an agricultural fungicide in large quantities worldwide; Limited industrial use in paints and plastics; [ACGIH]

Comments

The thiophthalimides include captan, captafol, and folpet; no systemic poisonings in humans have been reported; [EPA Pesticides] Allergic contact dermatitis in pesticide handlers is most likely due to maneb, carbofuran, carbaryl, captan, folpet, or captafol. [Marks, p. 312] TLV Basis is liver damage, kidney damage and dermal sensitization; A potential respiratory sensitizer; [ACGIH]

Captafol is no longer registered in the U.S. [EPA Pesticides]

Reference Link #1

Biomedical References

Yes

0.1 mg/m3, inhalable fraction and vapor (Surface Limit = 0.2 mg/100 cm2)

8E-09 mm Hg

Explanatory Notes

VP from HSDB;

Reference Link #2

Yes

Yes

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Yes

Probable (2a)

Anticipated human carcinogen

Confirmed Animal

Diseases

Occupational diseases associated with exposure to this agent:

• Asthma, occupational
• Contact dermatitis, allergic

Processes

Industrial Processes with risk of exposure:

• Farming (Pesticides)
• Painting (Pigments, Binders, and Biocides)