4-tert-Butylbenzoic acid

Agent Name
4-tert-Butylbenzoic acid
CAS Number
98-73-7
Formula
C11-H14-O2
Major Category
Other Classes
4-tert-Butylbenzoic acid formula graphical representation
Synonyms
Benzoic acid, 4-(1,1-dimethylethyl)-; Benzoic acid, 4-tert-butyl-; Benzoic acid, p-tert-butyl-; Kyselina p-terc.butylbenzoova [Czech]; TBBA; p-tert-Butylbenzoic acid; [ChemIDplus] PTBBA; [ACGIH] UN2811
Category
Benzoic Acid Derivatives
Description
Colorless or white solid; [CHEMINFO] Beige chips or powder; [MSDSonline]
Sources/Uses
Used to modify alkyd resins, to regulate polymerization of polyesters, and to inhibit corrosion; Used as an additive in cutting oils; [CHEMINFO]
Comments
"The TLV is based on testicular damage seen in acute and subacute animal studies." [ACGIH] A mild skin irritant; [HSDB] Toxic to the liver, kidneys, and peripheral nervous system in animals exposed to doses as low as 106 mg/m3 of dust over 7-11 days; [CHEMINFO] An irritant; Can be absorbed through skin; Effects in high-dose animal studies include convulsions, spastic paralysis with or without sensory change, and renal tubular damage; [MSDSonline] Danger of skin absorption; [MAK]
Biomedical References

Exposure Assessment

Skin Designation (ACGIH)
Yes
TLV (ACGIH)
0.1 mg/m3, inhalable fraction and vapor
MAK
2 mg/m3, inhalable fraction
Vapor Pressure
0.000636 mm Hg
Lethal Concentration
LC50 (rat) > 1,900 mg/m3/4h
Explanatory Notes
Flash point = 158 deg C; [CHEMINFO] The Guide in the Emergency Response Guidebook is for "Toxic solid, organic, n.o.s."

Adverse Effects

Neurotoxin
Other CNS neurotoxin
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
Reproductive Toxin
Yes

Diseases, Processes, and Activities Linked to This Agent

Processes

Industrial Processes with risk of exposure: