4-tert-Butylbenzoic acid

Synonyms

Benzoic acid, 4-(1,1-dimethylethyl)-; Benzoic acid, 4-tert-butyl-; Benzoic acid, p-tert-butyl-; Kyselina p-terc.butylbenzoova [Czech]; TBBA; p-tert-Butylbenzoic acid; [ChemIDplus] PTBBA; [ACGIH] UN2811

Category

Benzoic Acid Derivatives

Description

Colorless or white solid; [CHEMINFO] Beige chips or powder; [MSDSonline]

Sources/Uses

Used to modify alkyd resins, to regulate polymerization of polyesters, and to inhibit corrosion; Used as an additive in cutting oils; [CHEMINFO]

Comments

"The TLV is based on testicular damage seen in acute and subacute animal studies." [ACGIH] A mild skin irritant; [HSDB] Toxic to the liver, kidneys, and peripheral nervous system in animals exposed to doses as low as 106 mg/m3 of dust over 7-11 days; [CHEMINFO] An irritant; Can be absorbed through skin; Effects in high-dose animal studies include convulsions, spastic paralysis with or without sensory change, and renal tubular damage; [MSDSonline] Danger of skin absorption; [MAK]

Biomedical References

Yes

0.1 mg/m3, inhalable fraction and vapor

2 mg/m3, inhalable fraction

0.000636 mm Hg

LC50 (rat) > 1,900 mg/m3/4h

Explanatory Notes

Flash point = 158 deg C; [CHEMINFO] The Guide in the Emergency Response Guidebook is for "Toxic solid, organic, n.o.s."

Other CNS neurotoxin

Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion

Yes

Processes

Industrial Processes with risk of exposure:

• Metal Machining
• Painting (Pigments, Binders, and Biocides)