Agaritine
Agent Name
Agaritine
CAS Number
2757-90-6
Formula
C12-H17-N3-O4
Major Category
Biological Agents
Synonyms
Glutamic acid, 5-(2-(alpha-hydroxy-p-tolyl)hydrazide), L-; L-Glutamic acid, 5-(2-(4-(hydroxymethyl)phenyl)hydrazide); L-Glutamic acid, 5-(2-(alpha-hydroxy-para-tolyl)hydrazide); beta-N-(gamma-L(+)Glutamyl)4-hydroxymethylphenylhydrazine; beta-N-(alpha-L-Glutamyl)-4-hydroxymethylphenylhydrazine; [ChemIDplus]
Category
Mushroom Toxins
Description
Solid; [Merck Index]
Sources/Uses
Natural substance in several mushrooms in the Agaricus species, consumed both raw and cooked throughout the world; [IARC] A natural and edible constituent of commercial mushrooms; [Merck Index]
Comments
Adverse effects to mice after single injections of up to 400 mg/kg were excitation, seizures, and paralysis with histopathological evidence of injury to the liver, kidneys, bladder and lungs;; No data in humans; Inadequate evidence of carcinogenicity in animals; [IARC] Highly toxic; [CAMEO]
Biomedical References
Adverse Effects
Neurotoxin
Other CNS neurotoxin
Hepatotoxin
Hepatoxic (a) from occupational exposure (secondary effect) or (b) in animal studies or in humans after ingestion
IARC Carcinogen
Not classifiable
Diseases, Processes, and Activities Linked to This Agent
Other Information
No other related information on this agent was found.